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270107 VO Analysis of drugs and toxins II (2005W)
Analysis of drugs and toxins II: Stereochemical aspects and clinical relevance
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Vorbesprechung: Dienstag, 4.10.2005, 10:15 Uhr, UZB, HS III
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Principles of stereochemistry, impact on biological action
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F214, LA-Ch232
Last modified: Fr 31.08.2018 08:55
Content: Basic principles of stereochemistry (nomenclature, chiral elements); Impact of stereochemistry on biological action; Stereochemistry of drug-protein interaction; Stereo-selectivity in pharmacodynamics; Stereoselectivity in pharmacokinetics including pharmacogenetics; Concepts of enantiomer separation; Indirect liquid chromatographic enantiomer separation; Enantioselective capillary electrophoresis (CE) and chiral selectors for CE; Direct liquid chromatographic enantiomer separation including discussion of chiral stationary phases; Gas chromatographic enantiomer separation; Applications of enantiomer separation methods.