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270265 VO Biosynthesis of Natural Products (2007S)

Biosynthesis of Natural Products

1.00 ECTS (1.00 SWS), SPL 27 - Chemie

Blocklehrveranstaltung in der ersten Semesterhälfte,
8 Doppelstunden jeweils Di. 8:15-10:00, HS III

Details

Language: German

Lecturers

Friedrich Hammerschmidt

Classes

Currently no class schedule is known.

Information

Aims, contents and method of the course

Primary and secondary metabolism, techniques and reactions of general importance for biosynthesis, isotopic labelling, presentation of representatives of classes of natural products - polyketides: fatty acids, prostaglandins, griseofulvin, flavonoids, erynthromycin-A and monensin;
isoprenoids: isoprene rule, mevalonic acid, condensation of dimethylally- and isopentenyl diphosphate, squalene, ß-corotene, camphor, lanosterol, cyloartenol, cholesterol and steroid hormones;
alkaloids: nicotine, codeine, morphine;
shikimic acid pathway and ß-lactam antibiotics.

Assessment and permitted materials

Minimum requirements and assessment criteria

Understanding of stepwise biosynthesis of natural products from simple precursors; understanding of simplicity of reactions underlying complexity of natural products.

Examination topics

Reading list

: D. O¿Hagan, The Polyketide Metabolism, Ellis Horwood, 1991;
Übersichtsartikel.

Association in the course directory

F261

2.6. Organic Chemistry

27.01. Diploma Programme Chemistry

Last modified: Fr 31.08.2018 08:55