Warning! The directory is not yet complete and will be amended until the beginning of the term.
300091 SE Palaeogenomics (2017W)
Continuous assessment of course work
Labels
Registration/Deregistration
Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
- Registration is open from Th 07.09.2017 08:00 to Th 21.09.2017 18:00
- Deregistration possible until Tu 31.10.2017 18:00
Details
max. 15 participants
Language: English
Lecturers
Classes (iCal) - next class is marked with N
- Monday 09.10. 11:00 - 11:30 Konferenzzimmer (Kickoff Class)
- Tuesday 17.10. 12:00 - 13:30 Konferenzzimmer
- Tuesday 24.10. 12:00 - 13:30 Konferenzzimmer
- Tuesday 31.10. 12:00 - 13:30 Konferenzzimmer
- Tuesday 07.11. 12:00 - 13:30 Konferenzzimmer
- Tuesday 14.11. 12:00 - 13:30 Konferenzzimmer
- Tuesday 21.11. 12:00 - 13:30 Konferenzzimmer
- Tuesday 28.11. 12:00 - 13:30 Konferenzzimmer
- Tuesday 05.12. 12:00 - 13:30 Konferenzzimmer
- Tuesday 12.12. 12:00 - 13:30 Konferenzzimmer
- Tuesday 09.01. 12:00 - 13:30 Konferenzzimmer
- Tuesday 16.01. 12:00 - 13:30 Konferenzzimmer
- Tuesday 23.01. 12:00 - 13:30 Konferenzzimmer
- Tuesday 30.01. 12:00 - 13:30 Konferenzzimmer
Information
Aims, contents and method of the course
Assessment and permitted materials
Continuous Assessment (seminar attendance and participation: 10 marks, seminar presentations: 40 marks; essay: 50 marks). Total Marks 100.
Compulsory Elements: Attendance and continuous assessment
Compulsory Elements: Attendance and continuous assessment
Minimum requirements and assessment criteria
Examination topics
Reading list
Main textbook: Mark Jobling et al. 2014, Human evolutionary genetics: origins, peoples & disease 2nd edition.Allentoft ME, Sikora M, Sjogren KG, Rasmussen S, Rasmussen M, and Stenderup J. 2015. Population genomics of Bronze Age Eurasia. Nature 522.
Aoki K. 2015. Modeling abrupt cultural regime shifts during the Palaeolithic and Stone Age. Theoretical Population Biology 100:6-12.
Brandt G, Haak W, Adler CJ, Roth C, Szécsényi-Nagy A, Karimnia S, Möller-Rieker S, Meller H, Ganslmeier R, Friederich S et al. . 2013. Ancient DNA Reveals Key Stages in the Formation of Central European Mitochondrial Genetic Diversity. Science 342(6155):257-261.
Broushaki F, Thomas MG, Link V, López S, van Dorp L, Kirsanow K, Hofmanová Z, Diekmann Y, Cassidy LM, Díez-del-Molino D et al. . 2016. Early Neolithic genomes from the eastern Fertile Crescent. Science.
Cassidy LM, Martiniano R, Murphy EM, Teasdale MD, Mallory J, Hartwell B, and Bradley DG. 2016. Neolithic and Bronze Age migration to Ireland and establishment of the insular Atlantic genome. Proceedings of the National Academy of Sciences 113(2):368-373.
Fan S, Hansen MEB, Lo Y, and Tishkoff SA. 2016. Going global by adapting local: A review of recent human adaptation. Science 354(6308):54-59.
Fu Q. 2013. DNA analysis of an early modern human from Tianyuan Cave, China. Proc Natl Acad Sci USA 110:2223-2227.
Fu Q, Hajdinjak M, Moldovan OT, Constantin S, Mallick S, Skoglund P, Patterson N, Rohland N, Lazaridis I, Nickel B et al. . 2015. An early modern human from Romania with a recent Neanderthal ancestor. Nature 524(7564):216-219.
Fu Q, Li H, Moorjani P, Jay F, Slepchenko SM, Bondarev AA, Johnson PLF, Aximu-Petri A, Prufer K, de Filippo C et al. . 2014. Genome sequence of a 45,000-year-old modern human from western Siberia. Nature 514(7523):445-449.
Fu Q, Posth C, Hajdinjak M, Petr M, Mallick S, Fernandes D, Furtwängler A, Haak W, Meyer M, Mittnik A et al. . 2016. The genetic history of Ice Age Europe. Nature advance online publication.
Gamba C, Hanghøj K, Gaunitz C, Alfarhan AH, Alquraishi SA, Al-Rasheid KAS, Bradley DG, and Orlando L. 2015. Comparing the performance of three ancient DNA extraction methods for high-throughput sequencing. Molecular Ecology Resources:n/a-n/a.
Gamba C, Jones ER, Teasdale MD, McLaughlin RL, Gonzalez-Fortes G, Mattiangeli V, Domboróczki L, Kővári I, Pap I, Anders A et al. . 2014. Genome flux and stasis in a five millennium transect of European prehistory. Nat Commun 5:1-9.
Green RE. 2010. A draft sequence of the Neandertal genome. Science 328:710-722.
Gronau I, Arbiza L, Mohammed J, and Siepel A. 2013. Inference of Natural Selection from Interspersed Genomic Elements Based on Polymorphism and Divergence. Molecular Biology and Evolution 30(5):1159-1171.
Haak W, Lazaridis I, Patterson N, Rohland N, Mallick S, and Llamas B. 2015. Massive migration from the steppe was a source for Indo-European languages in Europe. Nature 522.
Hofmanová Z, Kreutzer S, Hellenthal G, Sell C, Diekmann Y, Díez-del-Molino D, van Dorp L, López S, Kousathanas A, Link V et al. . 2016. Early farmers from across Europe directly descended from Neolithic Aegeans. Proceedings of the National Academy of Sciences 113(25):6886-6891.
Johannsen NN, Larson G, Meltzer DJ, and Vander Linden M. 2017. A composite window into human history. Science 356(6343):1118-1120.
Jones ER, Zarina G, Moiseyev V, Lightfoot E, Nigst PR, Manica A, Pinhasi R, and Bradley DG. 2017. The Neolithic Transition in the Baltic Was Not Driven by Admixture with Early European Farmers. Current Biology 27(4):576-582.
Kılınç Gülşah M, Omrak A, Özer F, Günther T, Büyükkarakaya Ali M, Bıçakçı E, Baird D, Dönertaş Handan M, Ghalichi A, Yaka R et al. . 2016. The Demographic Development of the First Farmers in Anatolia. Current Biology.
Additional will be given in class
Aoki K. 2015. Modeling abrupt cultural regime shifts during the Palaeolithic and Stone Age. Theoretical Population Biology 100:6-12.
Brandt G, Haak W, Adler CJ, Roth C, Szécsényi-Nagy A, Karimnia S, Möller-Rieker S, Meller H, Ganslmeier R, Friederich S et al. . 2013. Ancient DNA Reveals Key Stages in the Formation of Central European Mitochondrial Genetic Diversity. Science 342(6155):257-261.
Broushaki F, Thomas MG, Link V, López S, van Dorp L, Kirsanow K, Hofmanová Z, Diekmann Y, Cassidy LM, Díez-del-Molino D et al. . 2016. Early Neolithic genomes from the eastern Fertile Crescent. Science.
Cassidy LM, Martiniano R, Murphy EM, Teasdale MD, Mallory J, Hartwell B, and Bradley DG. 2016. Neolithic and Bronze Age migration to Ireland and establishment of the insular Atlantic genome. Proceedings of the National Academy of Sciences 113(2):368-373.
Fan S, Hansen MEB, Lo Y, and Tishkoff SA. 2016. Going global by adapting local: A review of recent human adaptation. Science 354(6308):54-59.
Fu Q. 2013. DNA analysis of an early modern human from Tianyuan Cave, China. Proc Natl Acad Sci USA 110:2223-2227.
Fu Q, Hajdinjak M, Moldovan OT, Constantin S, Mallick S, Skoglund P, Patterson N, Rohland N, Lazaridis I, Nickel B et al. . 2015. An early modern human from Romania with a recent Neanderthal ancestor. Nature 524(7564):216-219.
Fu Q, Li H, Moorjani P, Jay F, Slepchenko SM, Bondarev AA, Johnson PLF, Aximu-Petri A, Prufer K, de Filippo C et al. . 2014. Genome sequence of a 45,000-year-old modern human from western Siberia. Nature 514(7523):445-449.
Fu Q, Posth C, Hajdinjak M, Petr M, Mallick S, Fernandes D, Furtwängler A, Haak W, Meyer M, Mittnik A et al. . 2016. The genetic history of Ice Age Europe. Nature advance online publication.
Gamba C, Hanghøj K, Gaunitz C, Alfarhan AH, Alquraishi SA, Al-Rasheid KAS, Bradley DG, and Orlando L. 2015. Comparing the performance of three ancient DNA extraction methods for high-throughput sequencing. Molecular Ecology Resources:n/a-n/a.
Gamba C, Jones ER, Teasdale MD, McLaughlin RL, Gonzalez-Fortes G, Mattiangeli V, Domboróczki L, Kővári I, Pap I, Anders A et al. . 2014. Genome flux and stasis in a five millennium transect of European prehistory. Nat Commun 5:1-9.
Green RE. 2010. A draft sequence of the Neandertal genome. Science 328:710-722.
Gronau I, Arbiza L, Mohammed J, and Siepel A. 2013. Inference of Natural Selection from Interspersed Genomic Elements Based on Polymorphism and Divergence. Molecular Biology and Evolution 30(5):1159-1171.
Haak W, Lazaridis I, Patterson N, Rohland N, Mallick S, and Llamas B. 2015. Massive migration from the steppe was a source for Indo-European languages in Europe. Nature 522.
Hofmanová Z, Kreutzer S, Hellenthal G, Sell C, Diekmann Y, Díez-del-Molino D, van Dorp L, López S, Kousathanas A, Link V et al. . 2016. Early farmers from across Europe directly descended from Neolithic Aegeans. Proceedings of the National Academy of Sciences 113(25):6886-6891.
Johannsen NN, Larson G, Meltzer DJ, and Vander Linden M. 2017. A composite window into human history. Science 356(6343):1118-1120.
Jones ER, Zarina G, Moiseyev V, Lightfoot E, Nigst PR, Manica A, Pinhasi R, and Bradley DG. 2017. The Neolithic Transition in the Baltic Was Not Driven by Admixture with Early European Farmers. Current Biology 27(4):576-582.
Kılınç Gülşah M, Omrak A, Özer F, Günther T, Büyükkarakaya Ali M, Bıçakçı E, Baird D, Dönertaş Handan M, Ghalichi A, Yaka R et al. . 2016. The Demographic Development of the First Farmers in Anatolia. Current Biology.
Additional will be given in class
Association in the course directory
MAN 3, MAN W1
Last modified: Sa 22.10.2022 00:29
The course will involve lectures/seminars which will address the following topics: history of anthropological genetics, studies of genetic variation within and between past and present human populations from various world regions, introduction to human molecular biology and population genetics, , history of ancient DNA analysis and its application in quaternary science, physical anthropology and archaeology, phylogeography and the study of spatio-temporal patterns, the paleogenetics of archaic human species, archaeogenetics and the origins of agriculture, the study of demographic history, sex-specific admixture and migrations, and natural selection.The first half of each session will be a lecture, which will be followed by a presentation on 1-2 papers by a student, and a critical discussion of the presented paper/s.Learning Outcomes:• Understanding the evolution of human genetic variability
• Knowledge regarding anthropological genetics
• Understanding the use, scope and limitations of aDNA genomics
• Knowledge about the application of aDNA methods in the context of the origins of anatomically modern humans, the origins and spread of agriculture, and other prehistoric migrations/dispersals
• Knowledge of the most recent developments in this young discipline and some of the future directions