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300123 VO Gene expression (2014S)

Ort: IMBA/ HS, Dr.Bohrgasse 3, 1030 Wien.
Beginn: 4.3.2014
jeweils Di. 9.30 - 11.30 Uhr mit Ausnahme am 17.6. (10:15-11:45!

Weitere Infos: http://molekularebiologie.univie.ac.at/

Moodle

Details

Language: German

Examination dates

Lecturers

Classes

Currently no class schedule is known.

Information

Aims, contents and method of the course

Lecture Content:
1. Molecular mechanisms of transcriptional control in bacteria
- promoters and their recognition by RNA polymerase
- Mechanisms of transcriptional control of bacterial operons: activators, repressors, 2-component systems
2. Molecular mechanisms of transcriptional control in eukaryotes:
- Promotors of RNA Polymerases I, II and III
- methodology for the analysis of gene expression
- structure-function relationsships in transcription factors
- Transcriptional initiation general transkription factors and coactivators
- chromatin structure and its influence on transcriptional activity of RNA polymerase II
- signals and molecular mechanisms of transcription factor activation
3. RNA processing
- RNA splicing
- RNA stability in bacteria and eukaryots
4. Translation and translational control in in bacteria and eukaryots
- Regulation and function of initiation factors
- Translational elongation and reprogramming of the genetic code
- Translational termination and ribosome recycling
5. Protein transport in bacteria and eukaryots
- Protein import to organells
- Protein export from bacteria

Assessment and permitted materials

Written exam

Minimum requirements and assessment criteria

Insight and knowledge concerning fundamental principles and mechanisms of transciptional and posstranscriptional regulation of gene expression

Examination topics

Course

Reading list

Wird in der ersten Vorlesungsstunde des jeweiligen Vortragenden bekanntgegeben

Association in the course directory

B-BMB 2, B-BMG 4

Last modified: Mo 07.09.2020 15:43