Universität Wien

300585 VO Organic Chemistry for Molecular biology (2011S)

5.00 ECTS (3.00 SWS), SPL 30 - Biologie

Vorbesprechung und Beginn.: Di. 1.3.2011, 8:15 Uhr
Wenn es möglich ist, werden im Mai und Anfang Juni Doppelstunden eingeschoben, damit die Vorlesung früher beendet und die Prüfung früher abgehalten werden kann.

Eintragung vom 23. 3.: Es werden insgesamt 8 Vorlesungsstunden eingeschoben, sodass die letzte Vorlesungsstunde am Di 31 5. stattfindet, die Übungsdoppelstunde am Mo 6. 6. (10:15-12:00) und die Prüfung am Fr 10. 6. 11 (14:00-16:30, im Carl Auer von Welsbach Hörsaal!).

Zusätzliche Vorlesungsstunden, ebenfalls im Josef-Loschmidt-Hörsaal:
Do 24. und Do 31. 3., 8:15-10:00;
Do 7. 4., 13:15-15:00;
Di 12. 4. und Di 17. 5., 9:15-10:00.

Details

Language: German

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

  • Tuesday 01.03. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 07.03. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 08.03. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 15.03. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 21.03. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 22.03. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 28.03. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 29.03. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 04.04. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 05.04. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 11.04. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 12.04. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 02.05. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 03.05. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 09.05. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 10.05. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 16.05. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 17.05. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 23.05. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 24.05. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 30.05. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 31.05. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 06.06. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 07.06. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 20.06. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 21.06. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Monday 27.06. 10:15 - 12:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42
  • Tuesday 28.06. 08:15 - 09:00 Joseph-Loschmidt-Hörsaal Chemie EG Währinger Straße 42

Information

Aims, contents and method of the course

Recommended Book: Harold Hart -
"Organic Chemistry"

I: Saturated Hydrocarbons
IUPAC nomenclature, isomers, properties, conformation, halogenation of alkanes.

II. Unsaturated Hydrocarbons
Alkenes and cycloalkenes: Nomenclature, cis-trans isomers, structure, properties, synthesis, electrophilic addition of HBr, Br2, HOX, rule of Markownikow, hydroboration, nucleophilic addition to C=C bonds with an electron-withdrawing substituent, hydrogenation, oxygen transfer reactions.
Chirality: R/S and D/L nomenclature, absolute configuration, racemate, enantiomers, meso compounds, resolution.
Alkynes: Nomenclature, structure, properties, preparation and reactions.

III. Aromatic compounds
Resonance, resonance structures, aromaticity, nomenclature, electrophilic substitution in benzenes, I- and M-effect, directing effect of substituents.

IV. Halogenated alkanes
Nomenclature, properties, polyhalogenated compounds, preparation, SN1- and SN2-reaktions; E1- and E2-eliminations, organometallic compounds (Mg, Li); methylation in biosphere.

V. Alcohols, phenols, and ethers
Nomenclature, properties, synthesis and reactions of alcohols, oxidation of alcohols in the cell, phenols as antioxidants, quinone/hydroquinone; ethers.

VI. Aldehydes and ketones
Nomenclature, properties, synthesis, nucleophilic additions to the carbonyl group, addition of hydrogen cyanide, water, alcohols, formation of acetals, addition of hydrogen, organometallic compounds, nitrogen nucleophiles, oxidation of aldehydes, enolisation of aldehydes and ketones, aldol reaction and condensation.

VII. Carboxylic acids and derivatives
Nomenclature, properties, synthesis, acidity, nucleophilic substitutions at the carbonyl group of carboxylic acids and their derivatives, esters and thioesters, amides, reductions, addition of organometallic compounds to esters, Claisen condensation, reactions of thioesters in biochemistry.

VIII. Amines and related compounds
Nomenclature, structure, properties, synthesis, acylation, alkylation, reactions of amines with nitrous acid, dehydrogenation of amines in cell.
IX. Derivatives of carbonic and phosphoric acid
Phosgen, chloroformates, carbonates, urea.
Formation and reactions of ATP, activation of carboxylic acids.

X. Synthesis of polymers
General remarks, polymerisation, radical polymerisation, polycondensation, and polyaddition.

XI. Aminoacids, peptides, and proteins
Proteinogenic aminoacids, reactivity of SH group of cysteine, peptides, ninhydrin reaction, synthesis of peptides, protecting groups for amino and carboxyl group, formation of peptide bonds, proteins, determination of C- and N-terminal aminoacids, Sanger reagent, sequencing of proteins, Edmann degradation, structure and biosynthesis of proteins.

XII. Carbohydrates, nucleosides and nuleotides
Monosaccharides, nomeclature and stereochemistry, cyclic acetals, anomers, reactions of monosaccharides, disaccharides (maltose, cellobiose, lactose, saccharose), polysaccharides (starch, cellulose), nucleosides, and nucleotides.

Assessment and permitted materials

Minimum requirements and assessment criteria

Examination topics

Reading list

Association in the course directory

B-BMB 6, B-BMG 6B, BBB 3, BMG 5, M115

Last modified: Mo 07.09.2020 15:44