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301101 VO Epigenetics- From basic mechanisms to medical applications (2024W)
Labels
Registration/Deregistration
Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
Details
Language: English
Examination dates
Lecturers
- Gerda Egger
- Julia Arand
- Sabine Lagger
- Wolfgang Miller
- Matthias Ronald Schaefer
- Christian Seiser
- Mark Wossidlo
Classes
Termin: täglich 4.- 20.11.2024
Zeit: 16:30-18:00 Uhr
Ort: Großer Hörsaal Histologie, Schwarzspanierstrasse 17, 1090 Wien
Information
Aims, contents and method of the course
To provide an introduction into basic epigenetic mechanisms and illustrate the role of chromatin for regulating different physiological and developmental processes as well as its involvement in disease.1. IntroductionHistory of Epigenetics 2. Basic epigenetic mechanismsDNA methylationChromatin modificationsNon-coding RNARNA methylationEpitranscriptomics3. Epigenetic PhenomenaImprintingX-Chromosome inactivationPosition effect variegation/Drosophila Epigenetics 4. Techniques to study the epigenome5. Epigenetic signatures in development and differentiationReprogramming of the epigenome during germ cell formation and after fertilizationThe concept of cellular memory (Polycomb- Trithorax)6.Influence of the Environment / Epigenetic alterations in diseaseCancer epigenetics, Clinical implications Imprinting defectsComplex diseaseMouse models to study epigenetics7.Selfish genetic elements and the origin of epigenetic mechanisms8. Epigenetics in host-microbe interactions.
Assessment and permitted materials
Written exam.
Minimum requirements and assessment criteria
A minimum of 55% of the achievable points is necessary for a positive grade.
sehr gut 90-100%
gut 80-89%
befriedigend 70-79%
genügend 55-69%
nicht genügend 0-54%
sehr gut 90-100%
gut 80-89%
befriedigend 70-79%
genügend 55-69%
nicht genügend 0-54%
Examination topics
Contents of the course units, PDF of power point presentations on Moodle.
Reading list
Provided on Moodle.
Association in the course directory
MMB III-2a.,MMB III-3a.,PhD-MB 3, MMEI III, UF MA BU 01, UF MA BU 04,
Last modified: Fr 10.01.2025 08:26