Universität Wien
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301618 VO+SE Structural Biology II (2025S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie

Registration/Deregistration

Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).

Details

Language: English

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

SR 1/MPL, Dr.Bohrgasse 9, 1030 Wien
jeweils Do. 10-12 Uhr

  • Thursday 13.03. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 20.03. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 27.03. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 03.04. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 10.04. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 08.05. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 15.05. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 22.05. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 05.06. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 12.06. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien

Information

Aims, contents and method of the course

Thermodynamics - introduction
Thermodynamics - experimental determination of binding affinities with examples
Thermodynamics - protein folding/unfolding, differential scanning calorimetry
Analysis and validation of macromolecular 3D structures
Protein dynamics at different scales
Structural basis of allosteric regulation
Conformational selection versus induced fit
Periodic table of Protein complexes
The dark proteome intrinsically disordered proteins
Structural basis of affinity and specificity with examples
Reaction mechanisms as reaction kinetics

Assessment and permitted materials

Minimum requirements and assessment criteria

Minimum requirements and assessment criteria
Attendance and active participation during the lecture course, >60% correct answers of exam for passing grade.
Assessment criteria:
100-90%: excellent (1)
89-80%: good (2)
79-70%: satisfactory (3)
69-60%: sufficient (4)
< 59%: insufficient (5)

Examination topics

Contents of the lectures as given in the course lecture notes and handouts available on the Moodle.

Reading list

A list of possible textbooks will be presented in the first lecture. Additional references are given throughout the lectures.

Association in the course directory

BMB 9

Last modified: Fr 10.01.2025 00:02