320029 VO General principles of drug action and pharmakokinetics (2009S)
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Details
Language: German
Lecturers
Classes (iCal) - next class is marked with N
- Tuesday 03.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 04.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 10.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 11.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 17.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 18.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 24.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 25.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 31.03. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 01.04. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 21.04. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 22.04. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 28.04. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 29.04. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 05.05. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 06.05. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 12.05. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 13.05. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 19.05. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 20.05. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 26.05. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 27.05. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 03.06. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 09.06. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 10.06. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 16.06. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 17.06. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 23.06. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Wednesday 24.06. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Tuesday 30.06. 12:30 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
Information
Aims, contents and method of the course
Assessment and permitted materials
Minimum requirements and assessment criteria
To describe the general principles of drug action with focus on cellular and molecular mechanisms and signal transduction cascades. The course includes the mechanisms of drug absorption, distribution and elimination and pharmacokinetics.
Examination topics
Reading list
Association in the course directory
A225
Last modified: Sa 02.04.2022 00:27
Drug-receptor-interactions, classification of different targets for drug action (receptors, ion channels, enzymes, carrier molecules), structure and functions of selected receptors (ligand-gated ion channels, G-protein-coupled receptors, nuclear receptors, kinase-linked receptors), pharmacology of second messenger systems (e.g. the adenylate cyclase/cyclic AMP system and the phospholipase C/inositol phosphate system), interaction of ion channels with G-proteins, the molecular architecture of voltage gated ion channels, their function and pharmacological properties, the release of chemical mediators, routes of drug administration, absorption, distribution, elimination (phase I reactions, the cytochrome P450 system), phase II reactions, first pass effect, active drug metabolites, renal excretion, pharmacokinetics (including compartment models), the autonomic nervous system (cholinergic and noradrenergic transmission, transmission by purines and 5-hydroxytryptamin), peptides and proteins as drugs, nitric oxide, local hormones.