320039 VO Separation and analysis methods for organic drug compounds (2009S)
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Language: German
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Classes (iCal) - next class is marked with N
- Monday 02.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 04.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Friday 06.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Monday 09.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 11.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Friday 13.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Monday 16.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 18.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Friday 20.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Monday 23.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 25.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Friday 27.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Monday 30.03. 10:30 - 11:30 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 01.04. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Friday 03.04. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 22.04. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Friday 24.04. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 29.04. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 06.05. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Friday 08.05. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Wednesday 13.05. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Friday 15.05. 10:30 - 12:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
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A207
Last modified: Sa 02.04.2022 00:27
In the first part, analytical methods of particular relevance for pharmacy laboratories are presented, the second part deals with instrumental separation techniques with a focus on methods for the separation of classical (small-molecule) drug compounds.
Aim: Acquisition of basic knowledge on the qualitative analysis of drug compounds with methods available in a pharmacy laboratory (proof of identity for drug compounds); knowledge about principles of function, applicability, and limitations of instrumental separation techniques (focus on chromatographic methods).
Contents: Determination of elemental composition, solubility, precipitation reactions, color reactions, identification of functional groups in drug compounds, physical properties, analysis of medicinal products (extraction of drug compounds, separation procedures); principles of chromatographic methods (separation mechanisms, classification of methods, theories of the chrom. process); individual chrom. methods: thin layer chromatography (TLC), column chrom. (CC), high performance liquid chrom. (HPLC), gas chrom. (GC); for each method: characteristic features, instrumentation, development techniques, detection methods, sample preparation, derivatisation; pharmaceutical applications; determination of separation performance, quantitative aspects (quantitation of elution curves and inner chromatograms, employment of internal and external standards); validation of chromatographic methods; reiated methods (SFC, CE, CEC).
Preconditions: successful completion of courses of the first study section; examinations on lectures from the second study section (3rd and 4th semester) can be done anyway (cf. Studienplan).
Mode of examination: written examination