320067 VO Drug Metabolism: Introduction and clinical applica (2009S)
Grundlagen und klinische Anwendung
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A400
Last modified: Fr 31.08.2018 08:57
Introduction to phase I and phase II metabolism; substrates, inducers, inhibitors of cytochrom P450, glucuronosyltransferases, sulfotransferases, acetyltransferases and glutathion-S-transferases; in vitro/in vivo methods of drug metabolism; pharmakogenetics, enzymkinetics (Km, Vmax, Ki); prediction of drug-drug interactions (examples from the Austria Codex - problem-based learning).