Universität Wien

321010 VO Principles of Drug Synthesis - B6 (2018S)

7.00 ECTS (4.00 SWS), SPL 32 - Pharmazie

01.03.2018-30.04.2018
Montag - Freitag 09.45-11.15 Uhr HS 8!
KEINE VO am 07.05.2018!!

Moodle u: stream

Details

Language: German

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

  • Thursday 01.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 02.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 05.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 06.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 07.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 08.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 09.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 13.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 14.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 15.03. 09:45 - 11:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 16.03. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 19.03. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 20.03. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 21.03. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 22.03. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 23.03. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 09.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 10.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 11.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 12.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 13.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 17.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 18.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 19.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 20.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 23.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 24.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 25.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 26.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 27.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 30.04. 09:45 - 11:15 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG

Information

Aims, contents and method of the course

The objective of the course is to teach the student the basic principles of organic chemistry focuse on drug syntheses.
Atomic orbitals; covalent bondings, stereochemistry, chirality; saturated and unsaturated carbohydrates, alkyl halides, alcohols, phenols, ether, sulfur containing compounds, aldehydes, ketones, carboxylic acids and derivatives, carbonic acid and derivatives; M- and I-effects, organic acids and bases; nucleophilic substitution: SN1, SN2,SNi; rearrangement reactions of carbonium ions, hydride shift, allylic rearrangement, Wagner-Meerwein- and Pincol-rearrangement, Hoffmann-Schmidt-rearrangement, Baeyer-Villiger-reactin; elektrophilic and nucleophilic substitution reactions on aromatic compounds, reaktions of diazonium-compounds; additions on C=C-double bonds; Diels-Alder-reactions; addition reactions on C=O-groups: acetals as protecting groups, imines, enamines reductive amination, hydride- and Grignard-reactions; aldol- and Knoevenagel-reactions, Perkin- and benzoin condensation and benzilic acid rearrangement, Wittig- and Mannich-reaction; haloform-reaction, reactions of carboxylic acid derivatives, esterification – hydrolysis of carboxylic esters, Claisen- and Dieckmann-condensation, cleavage of b-Ketoestern; eliminations, Hoffmann-elimination; reactions of radicals: anti-Markownikoff-orientation, allylic halogenation, Kolbe-synthesis, acyloin-condensation, radical reactions on alkenes, Sandmayer-reaction; syntheses of heterocyclic compounds: fundamental principles, quinolines, cumarines, furanes, thiophenes, pyrroles, hydantoines, indoles, pyridines, dihydropyridines; functional group interconversion.

Assessment and permitted materials

Written Examination
Duration: 120 Min.

Minimum requirements and assessment criteria

Marks:
1 = 37-40 P 2 = 33-36 P 3 = 29-32 P 4 = 24-28 P 5 = < 24 P

Examination topics

Lecture

Reading list

"Wie funktionieren organische Reaktionen", P. Sykes, Verlag Chemie
"Reaktionsmechanismen der Organischen Chemie" P. Sykes, Verlag Chemie
"Lehrbuch der organischen Chemie", H. Beyer, S. Hirzel Verlag Stuttgart
"Chemie II", E. Ehlers, Deutscher Apothekerverlag
"Das Basiswissen der organischen Chemie", J. Bülle, A. Hüttermann, Thieme-Verlag
"Organische Chemie", H. Hart, L. E. Craine, D. J. Hart, C. M. Hadad, Wiley-VCH
"Organikum", Heinz Becker (Ed.), Wiley-VCH

Association in the course directory

A105, BA10

Last modified: Sa 02.04.2022 00:27