Universität Wien
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323115 VU NMR for Drug Design - MPS5 (2022S)

2.00 ECTS (1.00 SWS), SPL 32 - Pharmazie
Continuous assessment of course work

Registration/Deregistration

Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).

Details

Language: English

Lecturers

Classes

25.05 9:00-11:00 2D313
27.05 9:00-11:00 2D313
01.06 9:00-11:00 2D313
02.06 9:00-11:00 2D313
03.06 9:00-11:00 2D313
23.06 9:00-11:00 2D313
24.06 9:00-10:30 2D313

Information

Aims, contents and method of the course

Protein-ligand interactions are at the heart of drug discovery research. NMR spectroscopy is perfectly suited to identify and validate protein-ligand interactions. A large number of NMR experiments are available. They are very powerful, but may also have pitfalls and limitations.
In this lecture, we will present central experiments for NMR in drug discovery, and assess their strengths and reliabilities.
Furthermore, methods for subsequent characterization of the interaction such as quantitative KD determination, binding mode analysis, or structure determination will be covered if time allows.

Assessment and permitted materials

Active cooperation

Minimum requirements and assessment criteria

Active cooperation

Examination topics

Discussed scientific topics in the field of practical aspects of NMR for Drug Design in the form of short seminars.

Reading list

Understanding NMR spectroscopy (Keeler)
Protein NMR Spectroscopy (Cavanagh et al.)
200 and More NMR experiments (Braun and Berger)

Association in the course directory

Last modified: Tu 17.05.2022 07:49