Universität Wien
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330029 VO Nutrition and Gene Regulation (2012W)

3.00 ECTS (2.00 SWS), SPL 33 - Ernährungswissenschaften

Fr 19.10.2012, 09:00 bis 10:30 (SE 562)
Do 25.10.2012, 14:00 bis 15:30 (SE 562)
Fr 9.11.2012, 09:00 bis 10:30 (SE 560)
Fr 16.11.2012, 09:00 bis 10:30 (SE 562)
Do 6.12.2012, 14:00 bis 15:30 (SE 560)
Fr 7.12.2012, 09:00 bis 10:30 (SE 560)
Do 13.12.2012, 14:00 bis 15:30 (SE 562)
Fr 14.12.2012, 09:00 bis 10:30 (SE 560)
Fr 11.1.2013, 09:00 bis 10:30 (SE 562)
Do 17.1.2013, 14:00 bis 15:30 (SE 560)
Fr 18.1.2013, 09:00 bis 10:30 (SE 560)
Do 24.1.2013, 14:00 bis 15:30 (SE 562)
Fr 25.1.2013, 09:00 bis 10:30 (SE 562)
Do 31.1.2013, 14:00 bis 15:30 (SE 562)
Moodle

Details

max. 40 participants
Language: English

Examination dates

Lecturers

Classes

Currently no class schedule is known.

Information

Aims, contents and method of the course

Principles of gene regulation:
- Transcriptional regulation
- Post-transcriptional regulation
- Modifications of chromatin structure
- DNA sequence elements with regulatory characteristics
Transcription factors:
- DNA-binding
- Mechanisms of action
- Regulating the regulators
Introduction into nutrigenomics:
- Definition
- Aims
- Methods:
-- Assessment ot transcription factors (e.g. ELISA, EMSA, supershift assays)
-- Transkriptomics (DNA microarray, RT-PCR)
Effects of macronutrients on gene expression:
- Effects of fatty acids on gene expression and corresponding transcription factors
- Effects of carbohydrates and insulin on gene expression and corresponding transcription factors
- Effects of amino acids on gene expression and corresponding transcription factors
Effects of micronutrients on gene expression:
- Retinol
- Cholecalciferol
- Iron
- Copper
- Zinc
- Secondary metabolites of plants (phytochemicals)
Nutrients and gene regulation from the perspective of nutritional scienes and nutritional medicine, e.g.:
- Nutrients, gene regulation and obesity
- Nutrients, gene regulation and metabolic syndrome
- Nutrients, gene regulation and atherosclerosis
Future aspects

Assessment and permitted materials

Final written exam, 2h (combination of multiple choice, single choice, open questions)

Minimum requirements and assessment criteria

The students will understand
- the basic principles of gene regulation in humans,
- the role of transcription factors , their activation and regulation,
- the methods of nutrigenomics,
- how specific nutrients affect gene regulation and signal transduction as well as
- the specific transcription factors involved in these processes,
- the potential impact of these events on health and disease

Examination topics

Lectures on the topics listed above, power point presentations, disscussion of pertinent literature

Reading list

Power point presentations will be available via LMS
Journal articles and reviews on current topics of nutrigenomics after prior announcement

Association in the course directory

Last modified: Sa 02.04.2022 00:27