330029 VO Nutrition and Gene Regulation (2014W)
Labels
LV für Masterstudierende- Voraussetzung: Zulasseung zum Masterstudium
Details
max. 40 participants
Language: English
Examination dates
- Friday 07.11.2014 09:00 - 11:00 Seminarraum 2E562 Ernährungswissenschaften UZA II
- Monday 17.11.2014 13:00 - 15:00 Seminarraum 2E562 Ernährungswissenschaften UZA II
- Monday 15.12.2014 09:00 - 11:00 Seminarraum 2E562 Ernährungswissenschaften UZA II
- Thursday 16.04.2015 09:00 - 10:30 Seminarraum 2E562 Ernährungswissenschaften UZA II
Lecturers
Classes
LEHRVERANSTALTUNGS-TERMINE
MI 1.10.2014 14:30-16 Uhr SE Raum 562FR 3.10.2014 8:30-10 Uhr SE Raum 562
MO 6.10.2014 8:30-10 Uhr SE Raum 562
MI 8.10.2014 8:30-10 Uhr SE Raum 562
FR 10.10.2014 8:30-10 Uhr SE Raum 562
MO 13.10.2014 8:30-10 Uhr SE Raum 562
MI 15.10.2014 8:30-10 Uhr SE Raum 562
FR 17.10.2014 8:30-10 Uhr SE Raum 562
MO 20.10.2014 8:30-10 Uhr SE Raum 562
MI 22.10.2014 8:30-10 Uhr SE Raum 562
FR 24.10.2014 8:30-10 Uhr SE Raum 562
MO 27.10.2014 8:30-10 Uhr SE Raum 562
MI 29.10.2014 8:30-10 Uhr SE Raum 562
FR 31.10.2014 8:30-10 Uhr SE Raum 562
Information
Aims, contents and method of the course
Assessment and permitted materials
Final written exam, 90 min (multiple choice, minimum requirement: 60%)
Minimum requirements and assessment criteria
The students will understand
- the basic principles of gene regulation in humans,
- the role of transcription factors , their activation and regulation,
- the methods of nutrigenomics,
- how specific nutrients affect gene regulation and signal transduction as well as
- the specific transcription factors involved in these processes,
- the potential impact of these events on health and disease
- the basic principles of gene regulation in humans,
- the role of transcription factors , their activation and regulation,
- the methods of nutrigenomics,
- how specific nutrients affect gene regulation and signal transduction as well as
- the specific transcription factors involved in these processes,
- the potential impact of these events on health and disease
Examination topics
Lectures on the topics listed above, power point presentations, disscussion of pertinent literature
Reading list
Power point presentations will be available via LMS
Journal articles and reviews on current topics of nutrigenomics after prior announcement
Journal articles and reviews on current topics of nutrigenomics after prior announcement
Association in the course directory
Last modified: Sa 02.04.2022 00:27
- Transcriptional regulation
- Post-transcriptional regulation
- Modifications of chromatin structure
- DNA sequence elements with regulatory characteristics
Transcription factors:
- DNA-binding
- Mechanisms of action
- Regulating the regulators
Introduction into nutrigenomics:
- Definition
- Aims
- Methods:
-- Assessment ot transcription factors (e.g. ELISA, EMSA, supershift assays)
-- Transkriptomics (DNA microarray, RT-PCR)
Effects of macronutrients on gene expression:
- Effects of fatty acids on gene expression and corresponding transcription factors
- Effects of carbohydrates and insulin on gene expression and corresponding transcription factors
- Effects of amino acids on gene expression and corresponding transcription factors
Effects of micronutrients on gene expression:
- Retinol
- Cholecalciferol
- Iron
- Copper
- Zinc
- Secondary metabolites of plants (phytochemicals)
Nutrients and gene regulation from the perspective of nutritional scienes and nutritional medicine, e.g.:
- Nutrients, gene regulation and obesity
- Nutrients, gene regulation and metabolic syndrome
- Nutrients, gene regulation and atherosclerosis
Future aspects